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MD Eyes has created a natural approach to eye health, wellness and beauty. All MD Eyes products are completely free of preservatives and harmful chemicals. Our formulas are designed to gently restore and refresh your eyes, without the negative side effects commonly associated with eye drops and eye medications. Whether you are dealing with dry eyes, red eyes, blurry vision, or droopy eyes,
MD Eyes provides a safe and effective solution.
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Comparison Disclaimers
* Not covered by MSP or insurance. Approximate price per GoodRx.
** Super sensitive skin to makeup or skin care products can show irritation
*** Wait 15 minutes before you put in your contacts
Improvement of Symptoms
Fast
1 hour to 1 day
95% of patients improve
Slow
2 weeks to 1 month
15% of patients improve
Slowest
3 months
15% of patients improve
Average Cost
$175/month.
$675/month. *
$715/month. *
Dosing
1 or 2 times/day
2 times/day,
12 hrs apart
2 times/day,
12 hrs apart
Side Effects
NONE **
Burning, Redness, Blurry,
Metalic Taste, Loss of Taste
Burning, Red Eye, Pain,
Blurry Vision, Swelling
Formulation & Application Method
Cream applied
to eyelid skin surface
Eye drops inside the eye
Eye drops inside the eye
Mode of Action
Activates
natural tear production
Inhibits immune
system T cells
Suppresses immune
system T cells
Contact Lens Precautions
Can use while wearing contacts
Do NOT use while wearing contacts ***
Do NOT use while wearing contacts ***
Source of Medication & Active Ingredient
Natural herb
(Jaborandi/Pilocarpine)
from the Amazon Rainforest.
Lifitegrast
Synthesized in a laboratory
Fungus
(Trichoderma Polysporum)
Cyclosporine-A eye drops
In Use Since
The 1870's
July, 2016
October, 2003
Issue
ReTEAR
Xiidra
Restasis
* Not covered by MSP or insurance. Approximate price per GoodRx.
** Super sensitive skin to makeup or skin care products can show irritation
*** Wait 15 minutes after using Xiidra before you put in your contacts
*** Wait 15 minutes after using Restasis before you put in your contacts
ReTEAR
Improvement of Symptoms:
Fast
1 hour to 1 day
95% of patients improve
Average Cost:
$175/month
Dosing:
1 or 2 times per day
Side Effects:
None**
Formulation & Application:
Cream applied to the eyelid surface
Mode of Action:
Activates natural tear production
Contact Lens Precautions:
Can use while wearing contacts
Source of Medication & Active Ingredient:
Natural Herb - Jaborandi/Pilocarpine from the Amazon Rainforest
In Use Since:
The 1870's
Improvement of Symptoms:
Fast
1 hour to 1 day
95% of patients improve
Average Cost:
$175/month
Dosing:
1 or 2 times per day
Side Effects:
None**
Formulation & Application:
Cream applied to the eyelid surface
Mode of Action:
Activates natural tear production
Contact Lens Precautions:
Can use while wearing contacts
Source of Medication & Active Ingredient:
Natural Herb - Jaborandi/Pilocarpine from the Amazon Rainforest
In Use Since:
The 1870's
Compare
Improvement of Symptoms:
Slowest
3 months
15% of patients improve
Average Cost:
$715/month*
Dosing:
2 times per day,
12 hrs apart
Side Effects:
Burning, Red Eye, Pain,
Blurry Vision, Swelling
Formulation & Application:
Eye drops inside the eye
Mode of Action:
Suppresses immune
system T cells
Contact Lens Precautions:
Do NOT use while wearing contacts ***
Source of Medication & Active Ingredient:
Fungus
(Trichoderma Polysporum)
Cyclosporine-A eye drops
In Use Since:
2003
Compare
Improvement of Symptoms:
Slow
1 month
47-52% of patients improve
Average Cost:
$690/month*
Dosing:
2 sprays per day
12 hours apart
Side Effects:
Coughing & Sneezing
Nose & Throat Irritation
Formulation & Application:
Nasal Spray
Mode of Action:
Binds nose's nicotinic receptors
Trigeminimal nerve in nostril
Contact Lens Precautions:
Can spray into upper nose wearing contacts
Source of Medication & Active Ingredient:
Varenicline Synthesized in laboratory
In Use Since:
2021
Compare
Improvement of Symptoms:
Slow
2 Weeks
52% of patients improve
Average Cost:
$715/month*
Dosing:
4 times per day
1-2 eyedrops per eye
Use up to 2 weeks max
Side Effects:
Pain, stinging, blurry vision
Infection, cataract, glaucoma
Formulation & Application:
Eyedrops inside the eye
Mode of Action:
Suppresses immunity
Steroid suppresses immune response
Contact Lens Precautions:
Do NOT use while wearing contacts***
Source of Medication & Active Ingredient:
Loteprednol etabonate 0.25%
In Use Since:
2021
Compare
Improvement of Symptoms:
Slowest
3 months
16.6% patients improve
Average Cost:
$605/month*
Dosing:
2 times per day
12 hours apart
Side Effects:
Pain, redness, irritation
Eyelid redness, unrinary tract infection, headache
Formulation & Application:
Eyedrops inside the eye
Mode of Action:
Suppresses immune system T cells
Contact Lens Precautions:
Do NOT use while wearing contacts***
Source of Medication & Active Ingredient:
Fungus
Trichoderma Polysporum
Cyclosporine-A 0.09%
In Use Since:
2018
Compare
Improvement of Symptoms:
Slow
1 month
8-11% of patients improve
Average Cost:
$715/month*
Dosing:
2 times per day
12 hours apart
Side Effects:
Burning, stinging, redness, itchy
blurry vision, swelling
Formulation & Application:
Eyedrops inside the eye
Mode of Action:
Suppresses immune system T cells
Contact Lens Precautions:
Do NOT use while wearing contacts***
Source of Medication & Active Ingredient:
Fungus
Trichoderma Polysporum
Cyclosporine-A 0.1%
In Use Since:
2023
Compare
Active Ingredient:
Oxymetazoline/brimonidine skin cream
Improvement of Symptoms:Fast
5 to 20 minutes
Average Cost:
$150 for eye and skin soothing
Dosing:
Skin serum once a day to eyelid
Packaging:
Lid smoothening cool tip applicator
Side Effects:
None**
Formulation & Application:
SKIN conditioning serum ON EYELID SURFACE
Mode of Action:
Clears and whitens eyes
Contact Lens Precautions:
Can use while wearing contacts
Source of Medication:
Invented and used since 1961
In Use Since:
The 1961
Ophthalmic Use:
Used in Visene
Ease of Use:
Can use under eye shadowCompare
Compare
Active Ingredient:
Oxymetazoline eye drops
Improvement of Symptoms:Fast
5 to 20 minutes
Average Cost:
$258 NOT COVERED by insurance. Expensive compared to regular dry eye drops.
Dosing:
1 eyedrop 4 times a day
Packaging:
Eye Drop Vials
Side Effects:
Pain with using eyedrops, eye inflammation, eye redness, dry eye, blurred vision, eye irritation, and headache. Up to 5% incidence of side effects.
Formulation & Application:
EYE DROPS INSIDE THE EYE
Mode of Action:
Whitens eyes
Contact Lens Precautions:
Do NOT use while wearing contacts. Wait 15 minutes after using Upneeq before you put in your contacts
Source of Medication:
Invented and used since 1961
In Use Since:
The 1961
Ophthalmic Use:
Used in Visene
Ease of Use:
Smears eye makeup when using dropsCompare
Active Ingredient:
Brimonidine 0.025%
Improvement of Symptoms:Fast
5 to 20 minutes
Average Cost:
Is not covered by MSP or insurance. $220 average cost on Drugs.com*
Dosing:
3-4 times a day
Packaging:
Eye Drops
Side Effects:
PAIN, BURNING, BLURRY VISION, SWELLING*, TIRED & DROWSY.
Formulation & Application:
DROPS INSIDE THE EYE
Mode of Action:
Whitens eyes
Contact Lens Precautions:
Do NOT use while wearing contacts. Wait 15 minutes after using before you put in your contacts
Source of Medication:
Invented and used since 1961
Ophthalmic Since:
The 2001
Preservative Toxic Effect:
BENZALKONIUM CHLORIDE causes dryeye
VS
Active Ingredient:
Pilocarpine
Improvement of Symptoms:20 to 60 minutes
Average Cost:
$150. Is not covered by MSP or insurance, less expensive than Restasis & Xiidra
Dosing:
1 to 2 times a day, 12 hrs apart
Packaging:
SKIN SERUM
Side Effects:
NONE. *super sensitive skin to makeup or skin care products can show irritation
Formulation & Application:
SKIN SERUM ON EYELID SURFACE
Mode of Action:
Focus near vision without glasses
Contact Lens Precautions:
Can use while wearing contacts
Source of Medication:
Plant derived
In Use Since:
The 1961
Ophthalmic Use:
Over a century
Ease of Use:
Can use under eye shadowCompare
Compare
Active Ingredient:
Pilocarpine 1.25%
Improvement of Symptoms:5 to 30 minutes
Average Cost:
$275 for 1 month supply using up to 3-4 times/day as recommended. Not covered by MSP/insurance.
Dosing:
4 times a day
Packaging:
EYE DROPS
Side Effects:
Eye Pain, headache, brow pain, redness, blur, dim or dark vision
Formulation & Application:
EYE DROPS INSIDE THE EYE
Mode of Action:
Presbyopia treatment
Contact Lens Precautions:
Do NOT use while wearing contacts. Wait 15 minutes after using before you put in your contacts
Source of Medication:
Plant derived
In Use Since:
2021
Ophthalmic Use:
Over a century
Ease of Use:
Smears eye makeup when using drops
Preservative Toxic Effect:
BENZALKONIUM CHLORIDE causes dryeye
VS
Active Ingredient:
Oxymetazoline skin cream
Improvement of Symptoms:Fast: 5 to 20 minutes
Average Cost:
$150 LESS EXPENSIVE, not covered by MSP or insurance
Dosing:
Skin cream once a day to eyelid
Packaging:
Lid smoothening cool tip applicator
Side Effects:
NONE.
Formulation & Application:
SKIN SERUM ON EYELID SURFACE
Mode of Action:
Lifts low lying eyelids
Contact Lens Precautions:
Can use while wearing contacts
Source of Medication:
Invented and used since 1961
In Use Since:
1961
Ophthalmic Use:
Used in Visene
Ease of Use:
Can use under eye shadowCompare
Compare
Active Ingredient:
Pilocarpine 1.25%
Improvement of Symptoms:Fast: 5 to 20 minutes
Average Cost:
$258 NOT COVERED by insurance. Expensive compared to regular dry eye drops.
Dosing:
4 times a day
Packaging:
EYE DROPS VIALS
Side Effects:
Pain with using eyedrops, eye inflammation, eye redness, dry eye, blurred vision, eye irritation, and headache. Up to 5% incidence of side effects.
Formulation & Application:
EYE DROPS INSIDE THE EYE
Mode of Action:
Lifts low lying eyelids
Contact Lens Precautions:
Do NOT use while wearing contacts. Wait 15 minutes after using before you put in your contacts
Source of Medication:
Invented and used since 1961
In Use Since:
2020
Ophthalmic Use:
Used in Visene
Ease of Use:
Smears eye makeup when using drops
VS
Improvement of Symptoms:
Fast
1 hour to 1 day
95% of patients improve
Average Cost:
$175/month
Dosing:
1 or 2 times per day
Side Effects:
None**
Formulation & Application:
Cream applied to the eyelid surface
Mode of Action:
Activates natural tear production
Contact Lens Precautions:
Can use while wearing contacts
Source of Medication & Active Ingredient:
Natural Herb - Jaborandi/Pilocarpine from the Amazon Rainforest
In Use Since:
The 1870's
Compare
VS
Improvement of Symptoms:
Slow
2 weeks to 1 month
Average Cost:
$675/month
Dosing:
1 or 2 times per day
12 hours apart
Side Effects:
Burning, Redness, Blurry,
Metallic Taste, Loss of Taste
Formulation & Application:
Eye drops inside the eye
Mode of Action:
Inhibits immune system T cells
Contact Lens Precautions:
Do NOT use while wearing contacts ***
Source of Medication & Active Ingredient:
Lifitegrast Synthesized in a laboratory
In Use Since:
2016
Compare
Improvement of Symptoms:
Slowest
3 months
15% of patients improve
Average Cost:
$715/month*
Dosing:
2 times per day,
12 hrs apart
Side Effects:
Burning, Red Eye, Pain,
Blurry Vision, Swelling
Formulation & Application:
Eye drops inside the eye
Mode of Action:
Suppresses immune
system T cells
Contact Lens Precautions:
Do NOT use while wearing contacts ***
Source of Medication & Active Ingredient:
Fungus
(Trichoderma Polysporum)
Cyclosporine-A eye drops
In Use Since:
2003
Compare
Improvement of Symptoms:
Slow
1 month
47-52% of patients improve
Average Cost:
$690/month*
Dosing:
2 sprays per day
12 hours apart
Side Effects:
Coughing & Sneezing
Nose & Throat Irritation
Formulation & Application:
Nasal Spray
Mode of Action:
Binds nose's nicotinic receptors
Trigeminimal nerve in nostril
Contact Lens Precautions:
Can spray into upper nose wearing contacts
Source of Medication & Active Ingredient:
Varenicline Synthesized in laboratory
In Use Since:
2021
Compare
Improvement of Symptoms:
Slow
2 Weeks
52% of patients improve
Average Cost:
$715/month*
Dosing:
4 times per day
1-2 eyedrops per eye
Use up to 2 weeks max
Side Effects:
Pain, stinging, blurry vision
Infection, cataract, glaucoma
Formulation & Application:
Eyedrops inside the eye
Mode of Action:
Suppresses immunity
Steroid suppresses immune response
Contact Lens Precautions:
Do NOT use while wearing contacts***
Source of Medication & Active Ingredient:
Loteprednol etabonate 0.25%
In Use Since:
2021
Compare
Improvement of Symptoms:
Slowest
3 months
16.6% patients improve
Average Cost:
$605/month*
Dosing:
2 times per day
12 hours apart
Side Effects:
Pain, redness, irritation
Eyelid redness, unrinary tract infection, headache
Formulation & Application:
Eyedrops inside the eye
Mode of Action:
Suppresses immune system T cells
Contact Lens Precautions:
Do NOT use while wearing contacts***
Source of Medication & Active Ingredient:
Fungus
Trichoderma Polysporum
Cyclosporine-A 0.09%
In Use Since:
2018
Compare
Improvement of Symptoms:
Slow
1 month
8-11% of patients improve
Average Cost:
$715/month*
Dosing:
2 times per day
12 hours apart
Side Effects:
Burning, stinging, redness, itchy
blurry vision, swelling
Formulation & Application:
Eyedrops inside the eye
Mode of Action:
Suppresses immune system T cells
Contact Lens Precautions:
Do NOT use while wearing contacts***
Source of Medication & Active Ingredient:
Fungus
Trichoderma Polysporum
Cyclosporine-A 0.1%
In Use Since:
2023
Compare